Phyto-phospholipid complex: A tabular update
نویسندگان
چکیده
Phytoconstituents have been used in medicine science since ancient times due to their various pharmacological actions. But most of them (like flavanoids, terpenoids) are low in lipid solubility and have large molecular size due to complex multiple ring structure, causing poor absorption and poor bioavailability via oral route. The phytosome system of drug delivery results in increased bioavailability of these phytoconstituents. Phytosome are produced by a patented process where standardized plant extracts/phytoconstituents are bound to phospholipids (mostly phosphatidylcholine). The phytosome technology has been applied over many popular herbal drugs such as Ginkgo biloba, hawthorn, milk thistle, grape seed, green tea
منابع مشابه
Phyto-liposomes as nanoshuttles for water-insoluble silybin-phospholipid complex.
Among various phospholipid-mediated drug delivery systems (DDS) suitable for topic and oral administration, phytosome technology represents an advanced innovation, widely used to incorporate standardized bioactive polyphenolic phytoconstituents into phospholipid molecular complexes. In order to extend their potential therapeutic efficiency also to other routes of administration, we proposed a n...
متن کاملCrosstalk between Phospholipase D and Sphingosine Kinase in Plant Stress Signaling
The activation of phospholipase D (PLD) produces phosphatidic acid (PA), whereas plant sphingosine kinase (SPHK) phosphorylates long-chain bases to generate long-chain base-1-phosphates such as phytosphingosine-1-phosphate (phyto-S1P). PA and phyto-S1P have been identified as lipid messengers. Recent studies have shown that PA interacts directly with SPHKs in Arabidopsis, and that the interacti...
متن کاملNew Insights into Phospholipase D and Sphingosine Kinase Activation in Arabidopsis
initiated work in this regard with respect to different PA species (Guo et al., 2011). Additionally, it can be speculated that PA targets (see this review by Guo and Wang) can phosphorylate SPHKs, leading to their activation as previously shown in mammals (Pitson, 2010). Clearly, solving the SPHK structures will be crucial for understanding the regulatory mechanisms that control these enzymes. ...
متن کاملPhyto-Female Complex for the relief of hot flushes, night sweats and quality of sleep: randomized, controlled, double-blind pilot study.
OBJECTIVE To determine the efficacy and safety of the herbal formula Phyto-Female Complex (SupHerb, Netanya, Israel; ingredients: standardized extracts of black cohosh, dong quai, milk thistle, red clover, American ginseng, chaste-tree berry) for the relief of menopausal symptoms. METHODS A randomized, double-blind, placebo-controlled trial in 50 healthy pre and postmenopausal women, aged 44-...
متن کاملPassiflora: a review update.
This review describes the morphology, microscopy, traditional and folklore uses, phyto-constituents, pharmacological reports, clinical applications and toxicological reports of the prominent species of the genus Passiflora. Flavonoids, glycosides, alkaloids, phenolic compounds and volatile constituents have been reported as the major phyto-constituents of the Passiflora species. A few species o...
متن کامل